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KMID : 0941820180280040308
Korean Journal of Clinical Pharmacy
2018 Volume.28 No. 4 p.308 ~ p.319
Visual Analysis of Regional Variations in Antidepressant Use and Suicide Rat
Kim Ho-Jung

Lee Iyn-Hyang
Abstract
Background: Some mental illnesses such as depression are known to be one of the risk factors of suicide and properantidepressant therapy can reduce suicidal behavior.

Objectives: This study aimed to analyze regional variations in antidepressantconsumption and adherence, suicide rate, prevalence of suicide related mental disorders, and access to relevant healthcareservices.

Methods: Cross-sectional analyses were conducted using National Patients Sample data compiled by the HealthInsurance Review and Assessment Service between 2014 and 2016. We included patients who had a diagnosis record of suiciderelated mental disorders during the study period. Cause of death statistics and National health and medical statistics were used toidentify suicide rate and distribution of healthcare service. We conducted visual analyses, chi-squared tests, independent t-testsand correlation analyses to demonstrate regional variations.

Results: Between 2014 and 2016, the average prevalence of suiciderelated mental disorders was 5.4 per cent. Suicide rate and prevalence of suicide related mental disorders were higher in Gangwon,Chungcheong, and Jeolla (p < 0.001), and lower in Seoul (p < 0.001) than the national average. Unexpectedly, regional variationsin antidepressant consumption were seen in the limited area including Daejeon, Chungnam and Gyeongnam (p < 0.05). The numberof mild patient-centered clinics was associated positively with antidepressant consumption (p < 0.01) and associated negativelywith suicide rate (p < 0.01).

Conclusion: There were some regional variations in prevalence of suicide related mental disorders,antidepressant adherence and suicide rate. The higher level of antidepressant therapy and the lower level of suicide rates wereseen in regions with easy access to mild patient-centered clinics.
KEYWORD
Antidepressants, suicide, mental disorders, spatial analysis, Geographic Information Systems
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